Título / Title

ANGIOGRAPHY FOR OPTICAL COHERENCE TOMOGRAPHY (OCT-A) IN STARGARDT DISEASE IN TWO YOUNG PATIENTS: CASE REPORT

Introdução / Purpose

To observe and evaluate possible changes in the chorio-retinal microvasculature of two young patients diagnosed with Stargardt's Disease through the analysis of angiography by optical coherence tomography (OCT-A).

Material e Método / Methods

Analysis of vascularization of the choriocapillar and retina through optic coherence tomography angiography in young patients with Stargardt's disease

Resultados / Results

A 24-year-old white female patient from São Paulo/SP, with a history of progressive visual acuity in both eyes with about ten years of evolution. At the ophthalmological examination, visual acuity is presented for a distance with the best correction of 0.28 in the right eye and 0.33 in the left eye.
Optical Coherence Tomography Angiography in section of the choriocapillar layer showing small, hiporreflective confluent islands suggestive of poor perfusion in the foveal and perifoveal region.
A 28-year-old brown female patient from Itaguaí/RJ, with a history of low visual acuity progressive in both eyes with about 9 years of evolution, worsening after gestation. At the ophthalmologic examination, visual acuity is presented for a distance with the best correction of 0.05 in the right eye and 0.05 in the left eye.
Optical Coherence Tomography Angiography in section of the choriocapillar layer showing confluent islands hiporeflective, suggestive of poor perfusion in the foveal and perifoveal region.

Discussão e Conclusões / Conclusion

The evaluation of the choriocapillary layer by the OCT-A of these patients presents areas of ischemia in the foveal and perifoveal region. Observing this, it is possible that this ischemia may lead to dysfunction of the pigment epithelium of the retina and photoreceptors of the foveal region, consequently resulting in a low visual acuity, but further studies are necessary to ratify this statement in patients with Stargardt's Disease. In addition, new parameters are required to objectively characterize the decrease in vascular density in the choriocapillar region.

Palavras Chave

Stargardt; OCT-A